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Research

Publications

Ketscher, A., Jilg, CA., Willmann, D., Hummel, B., Imhof, A., Rüsseler, V., Hölz, S., Müller, JM., Metzger, E. and Schüle, R. (2014) LSD1 controls metastasis of androgen-independent prostate cancer cells through PXN and LPAR6. Oncogenesis 3, e120.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA (2014) Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix. Genes & Development 28: 2134-2150

Gatsi, R., Schulze, B., Rodriguez-Palero, M. J., Hernando-Rodriguez, B., Baumeister, R. & Artal-Sanz, M. (2014) Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans. PLoS One, 9(9), e107671.

Tholen M, Hillebrand LE, Tholen S, Sedelmeier O, Arnold SJ, Reinheckel T (2014) Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo. Nature communications 5: 4931

Moller Y, Siegemund M, Beyes S, Herr R, Lecis D, Delia D, Kontermann R, Brummer T, Pfizenmaier K, Olayioye MA (2014) EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells. PloS one 9: e107165

Wolf, T., Qi, W., Schindler, V., Runkel, E. D. & Baumeister, R. (2014) Doxycyclin ameliorates a starvation-induced germline tumor in C. elegans daf-18/PTEN mutant background. Exp Gerontol, 56, 114-22.

Weinberg F, Schulze E, Fatouros C, Schmidt E, Baumeister R, Brummer T. (2014) Expression pattern and first functional characterization of riok-1 in Caenorhabditis elegans. Gene Expr Patterns. 2014 Jul;15(2):124-34. doi: 10.1016/j.gep.2014.05.005. Epub 2014 Jun 12.

Videm P, Gunasekaran D, Schroder B, Mayer B, Biniossek ML, Schilling O (2014) Automated peptide mapping and protein-topographical annotation of proteomics data. BMC bioinformatics 15: 207

Duteil, D., Metzger,E., Willmann, D., Karagianni, P., Friedrichs, N., Greschik, H., Günther,T., Buettner, R., Talianidis, I., Metzger, D. and Schüle, R. (2014) LSD1 promotes oxidative metabolism of white adipose tissue. Nat. Commun. 5, 4093 doi: 10.1038/ncomms5093.

Kotkamp, K., Kur, E., Wendik, B., Polok, B.K., Ben-Dor, S., Onichtchouk, D., and Driever, W. (2014). Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation. PLoS ONE 9, e92356.

Zhu, D., Holz, S., Metzger, E., Pavlovic, M., Jandausch, A., Jilg, C., Galgoczy, P., Herz, C., Moser, M., Metzger, D., Gunther, T., Arnold, S. J.* & Schule, R.* (2014) Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells. Nat Commun, 5, 3174.*corresponding authors

Anke Augspach, Joachim H. List, Philipp Wolf, Heike Bielek, Carsten Schwan, Ursula Elsässer-Beile, Klaus Aktories and Gudula Schmidt (2013) Activation of RhoA,B,C by Yersinia Cytotoxic Necrotizing Factor (CNFy) Induces Apoptosis in LNCaP Prostate Cancer Cells. Toxins 2013, 5, 2241-2257

Bedzhov I, Alotaibi H, Basilicata MF, Ahlborn K, Liszewska E, Brabletz T, Stemmler MP. (2013) Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency. Stem Cell Res. 2013 Nov;11(3):1250-63. doi: 10.1016/j.scr.2013.08.009

Jankovic D, Ganesan J, Bscheider M, NStickel N, Weber F, Guarda G, Follo M, Pfeifer D, Tardivel A, Ludigs K, Bouazzaoui A, Kerl K, Fischer J, Haas T, Schmitt-Gräff A, Manoharan A, Müller L, Finke J, Martin S, Gorka O, Peschel C, Ruland J, Idzko M, Duyster J, Holler E, French LE, Poeck H, Contassot E, Zeiser R. (2013). The Nlrp3-inflammasome regulates acute graft-versus-host disease. Journal of Experimental Medicine 210:1899-910, 2013.

Groot, A.J., Cobzaru, C., Weber, S., Saftig, P., Blobel, C.P., Kopan, R., Vooijs, M., and Franzke, C.-W. (2013). Epidermal ADAM17 Is Dispensable for Notch Activation. The Journal of Investigative Dermatology 9–11.

Siebzehnrubl, F.A., Silver, D.J., Tugertimur, B., Deleyrolle, L.P., Siebzehnrubl, D., Sarkisian, M.R., Devers, K.G., Yachnis, A.T., Kupper, M.D., Neal, D., Nabilsi, N.H., Kladde, M.P., Suslov, O., Brabletz, S., Brabletz, T., Reynolds, B.A., Steindler, D.A. (2013). The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Mol.Med. 5(8):1196-212.